Central venous catheter-associated fungemia due to Wangiella dermatitidis.

Abstract

Central venous catheter-related Wangiella dermatitidis infection has been increasingly reported in the recent literature. We report a case of central venous catheter (Port-A-Cath)-related fungemia caused by W. dermatitidis in a 58-year-old woman with lung cancer. Two W. dermatitidis isolates were recovered from 2 blood samples drawn from a peripheral vein and the Port-A-Cath 4 months after its placement. The minimum inhibitory concentrations of 2 isolates to fluconazole and amphotericin B using the standard broth microdilution method were 48 microg/mL and 0.19 microg/mL, respectively. The Port-A-Cath was removed and the fungemia responded to amphotericin B treatment. W. dermatitidis should be categorized as a pathogen that can cause central venous catheter-associated fungemia, particularly in immunocompromised patients.

• Authors: Ping-Huei Tseng, Peilin Lee, Tzu-Hsiu Tsai, Po-Ren Hsueh
• Journal: Journal of the Formosan Medical Association = Taiwan yi zhi (J Formos Med Assoc) Vol. 104 Issue 2 Pg. 123-6 (Feb 2005) ISSN: 0929-6646 [Print] Singapore
• PMID: 15765168 (Publication Type: Case Reports, Journal Article)

Topics

• Catheterization, Central Venous (adverse effects)
• Exophiala (isolation & purification)
• Female
• Fungemia (etiology)
• Humans
• Immunocompromised Host
• Middle Aged
• Mycoses (microbiology)