[Therapeutic effects of calcitonin on back pain in the patients with osteoporosis].

A prospective study was performed to clarify the therapeutic effect on calcitonin in the patients with osteoporosis using patient-based outcome measures. A total of 67 patients with primary osteoporosis who complained back pain were included in this study. All patients were administered calcitonin 20 Unit/week intramuscularly. The therapeutic effects were assessed using various patient-based outcome measures before treatment, 2, 4 weeks and 3 months after treatment. We used Short form 12 for measuring general well-being, Roland Morris disability questionnaire for functional status associated with back pain, and visual analogue scale for pain intensity. Statistic analysis was performed using paired-t test. Pain intensity and functional status were significantly recovered at 2 weeks follow-up time and the effects were continued at 3 months follow-up time. Physical component summary (PCS) was recovered at 3 months follow-up tme, whereas mental component summary (MCS) was improved at 2 weeks follow-up time. These facts suggest that improvement of back pain using calcitonin correlates directly with recovery in functional status, indirectly with recovery in general well being.
AuthorsShin-ichi Konno, Shin-ichi Kikuchi
JournalClinical calcium (Clin Calcium) Vol. 15 Issue 3 Pg. 168-73 (Mar 2005) ISSN: 0917-5857 [Print] Japan
PMID15741698 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Calcitonin
  • Aged
  • Aged, 80 and over
  • Calcitonin (therapeutic use)
  • Female
  • Humans
  • Low Back Pain (drug therapy)
  • Middle Aged
  • Osteoporosis, Postmenopausal (physiopathology)
  • Prospective Studies
  • Treatment Outcome

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!

Choose Username:
Verify Password: