Rhabdoid meningioma occurring in an unrelated resection cavity with leptomeningeal carcinomatosis. Case report.

Abstract

Rhabdoid meningioma (RM) is a recently described, aggressive variant of meningioma. The authors report a case of RM occurring in the resection cavity of an unrelated neurosurgical procedure, temporal lobectomy for intractable seizures. The patient presented with intractable headache 10 years after the temporal lobectomy. Imaging revealed a dura-based, uniformly enhancing lesion within the resection cavity. She underwent gross-total resection and the findings of the surgical pathological report were consistent with an RM, with a dramatically elevated MIB-1 index of approximately 50%. The patient's clinical course was complicated by severe pain and communicating hydrocephalus secondary to rapid dissemination of malignant cells throughout the CSF pathways. Despite aggressive measures, including tumor resection, ventriculoperitoneal shunt placement, and the initiation of conventional radiation therapy, the ensuing leptomeningeal carcinomatosis proved to be rapidly fatal.

• Authors: Marthew A Koenig, Romergryko G Geocadin, Piotr Kulesza, Alessandro Olivi, Henry Brem
• Journal: Journal of neurosurgery (J Neurosurg) Vol. 102 Issue 2 Pg. 371-5 (Feb 2005) ISSN: 0022-3085 [Print] United States
• PMID: 15739568 (Publication Type: Case Reports, Journal Article)

Chemical References

• Ki-67 Antigen

Topics

• Adult
• Anterior Temporal Lobectomy
• Combined Modality Therapy
• Cranial Irradiation
• Epilepsy, Complex Partial (pathology, surgery)
• Fatal Outcome
• Female
• Humans
• Ki-67 Antigen (analysis)
• Meningeal Neoplasms (pathology, radiotherapy, surgery)
• Meningioma (pathology, radiotherapy, secondary, surgery)
• Neoplasm Invasiveness
• Neoplasm, Residual (pathology, radiotherapy, surgery)
• Postoperative Complications (pathology, surgery)
• Puerperal Disorders (pathology, surgery)
• Radiotherapy, Adjuvant
• Reoperation
• Spinal Cord Neoplasms (pathology, secondary)