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[A-leukemic caecal myeloid sarcoma: a difficult diagnosis].

Abstract
Myeloid sarcoma is a malignant neoplasia composed of abnormal myeloid or monocytic cells, often localized in bones, but also rarely in extra-medullary sites such as lymph nodes, skin and soft tissue. We report a case of caecal myeloid sarcoma, diagnosed in a 60 year old woman who complained from abdominal pain and weight loss, in absence of any medullary disorder. Initially misdiagnosed as a B lymphoma because of a weak positivity for CD79a, the diagnosis of primitive caecal myeloid sarcoma was eventually established after further investigations showing a positivity for lysozyme and myeloperoxidase. This report of such a rare clinical and pathological presentation of a myeloid sarcoma underlines a difficult differential diagnosis for which adequate immunohistochemistry, including lysozyme and myeloperoxydase is mandatory.
AuthorsMarie-Cécile Nollevaux, Monique Delos, Henri Noël, Anne Sonet, Alain Rosière, Ivan Théate
JournalAnnales de pathologie (Ann Pathol) Vol. 24 Issue 5 Pg. 436-9 (Oct 2004) ISSN: 0242-6498 [Print] France
Vernacular TitleLocalisation caecale d'un sarcome myéloïde a-leucémique: un diagnostic difficile.
PMID15738870 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antigens, CD
  • CD79 Antigens
  • CD79A protein, human
  • Receptors, Antigen, B-Cell
  • Peroxidase
  • Muramidase
Topics
  • Abdominal Pain
  • Antigens, CD (analysis)
  • CD79 Antigens
  • Cecal Neoplasms (diagnosis, pathology)
  • Diagnosis, Differential
  • Female
  • Humans
  • Immunohistochemistry
  • Leukemia, Myeloid (diagnosis, pathology)
  • Middle Aged
  • Muramidase (analysis)
  • Peroxidase (analysis)
  • Receptors, Antigen, B-Cell (analysis)
  • Weight Loss

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