Abstract |
Myeloid sarcoma is a malignant neoplasia composed of abnormal myeloid or monocytic cells, often localized in bones, but also rarely in extra-medullary sites such as lymph nodes, skin and soft tissue. We report a case of caecal myeloid sarcoma, diagnosed in a 60 year old woman who complained from abdominal pain and weight loss, in absence of any medullary disorder. Initially misdiagnosed as a B lymphoma because of a weak positivity for CD79a, the diagnosis of primitive caecal myeloid sarcoma was eventually established after further investigations showing a positivity for lysozyme and myeloperoxidase. This report of such a rare clinical and pathological presentation of a myeloid sarcoma underlines a difficult differential diagnosis for which adequate immunohistochemistry, including lysozyme and myeloperoxydase is mandatory.
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Authors | Marie-Cécile Nollevaux, Monique Delos, Henri Noël, Anne Sonet, Alain Rosière, Ivan Théate |
Journal | Annales de pathologie
(Ann Pathol)
Vol. 24
Issue 5
Pg. 436-9
(Oct 2004)
ISSN: 0242-6498 [Print] France |
Vernacular Title | Localisation caecale d'un sarcome myéloïde a-leucémique: un diagnostic difficile. |
PMID | 15738870
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Antigens, CD
- CD79 Antigens
- CD79A protein, human
- Receptors, Antigen, B-Cell
- Peroxidase
- Muramidase
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Topics |
- Abdominal Pain
- Antigens, CD
(analysis)
- CD79 Antigens
- Cecal Neoplasms
(diagnosis, pathology)
- Diagnosis, Differential
- Female
- Humans
- Immunohistochemistry
- Leukemia, Myeloid
(diagnosis, pathology)
- Middle Aged
- Muramidase
(analysis)
- Peroxidase
(analysis)
- Receptors, Antigen, B-Cell
(analysis)
- Weight Loss
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