Optical coherence tomography in Best's disease: an observational case report.

Abstract

PURPOSE:

To report the optical coherence tomographic (OCT) findings in a case of Best's disease.

DESIGN:

Observational case report.

METHODS:

Optical coherence tomography was carried out to understand the pathogenesis of Best's disease in a 13-year-old girl.

RESULTS:

Optical coherence tomography demonstrated that the lipofuscin accumulated in a cystic space underneath the retinal pigment epithelium in the "pseudohypopyon stage" of Best's disease. It also demonstrated the disruption of the photoreceptors in the "scrambled egg" stage.

CONCLUSIONS:

These new OCT findings could explain the retention of good visual acuity in the "pseudohypopyon stage" and the loss of visual acuity in the "scrambled egg" stage of Best's disease.

• Authors: Vasumathy Vedantham, Kim Ramasamy
• Journal: American journal of ophthalmology (Am J Ophthalmol) Vol. 139 Issue 2 Pg. 351-3 (Feb 2005) ISSN: 0002-9394 [Print] United States
• PMID: 15734003 (Publication Type: Case Reports, Journal Article)

Chemical References

• Lipofuscin

Topics

• Adolescent
• Diagnostic Techniques, Ophthalmological
• Female
• Humans
• Lipofuscin (metabolism)
• Macular Degeneration (diagnosis, metabolism)
• Pigment Epithelium of Eye (metabolism, pathology)
• Retina (metabolism, pathology)
• Tomography, Optical Coherence (methods)