Abstract | BACKGROUND: OBJECTIVE: This study was undertaken to determine whether intestinal inflammation alters fecal elastase concentration in dogs. METHODS: Fecal elastase concentration was measured with an ELISA kit in the following groups of dogs: group 1 (n=16), control dogs, without gastrointestinal disease; group 2 (n=14), dogs with diarrhea and no histopathologic evidence of intestinal inflammation; and group 3 (n=12), dogs with diarrhea and histopathologic evidence of intestinal inflammation. Serum trypsin-like immunoreactivity (TLI) was determined in dogs with diarrhea to rule out EPI. RESULTS: All dogs in groups 2 and 3 had serum TLI concentrations >5 microg/L, ruling out EPI. No statistically significant difference was found in fecal elastase concentration among the 3 groups of dogs (P=.969). CONCLUSIONS:
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Authors | I A Battersby, I R Peters, M J Day, A J German, E J Hall |
Journal | Veterinary clinical pathology
(Vet Clin Pathol)
Vol. 34
Issue 1
Pg. 49-51
( 2005)
ISSN: 0275-6382 [Print] United States |
PMID | 15732018
(Publication Type: Journal Article)
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Chemical References |
- Reagent Kits, Diagnostic
- Pancreatic Elastase
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Topics |
- Animals
- Diarrhea
(enzymology, veterinary)
- Dog Diseases
(enzymology)
- Dogs
- Enzyme-Linked Immunosorbent Assay
(veterinary)
- Exocrine Pancreatic Insufficiency
(diagnosis, veterinary)
- Feces
(enzymology)
- Female
- Inflammatory Bowel Diseases
(enzymology, veterinary)
- Male
- Pancreatic Elastase
(analysis)
- Reagent Kits, Diagnostic
(veterinary)
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