Resolution of peanut allergy following bone marrow transplantation for primary immunodeficiency.

Abstract

Peanut allergy is a severe and life-threatening form of food allergy. Treatments are being developed but the mainstays of current management remain avoidance of peanut and appropriate use of rescue medication. We report the case of a boy with peanut allergy who required a bone marrow transplant (BMT) for combined immunodeficiency. A food challenge, 2 years after transplant, showed that his peanut allergy had resolved. Allergic disorders constitute a form of immune deviation and while we do not advocate BMT as a treatment for peanut allergy, we believe this case provides an insight into the basic mechanisms involved in food allergy.

• Authors: J O'B Hourihane, H L Rhodes, A M Jones, P Veys, G J Connett
• Journal: Allergy (Allergy) Vol. 60 Issue 4 Pg. 536-7 (Apr 2005) ISSN: 0105-4538 [Print] Denmark
• PMID: 15727591 (Publication Type: Case Reports, Journal Article)

Topics

• Bone Marrow Transplantation
• Child
• Humans
• Immunologic Deficiency Syndromes (surgery)
• Male
• Peanut Hypersensitivity (physiopathology)
• Postoperative Period
• Remission Induction