[Caveolae/caveolins and virus infection].

Abstract

Caveolae, whose major structural proteins are Caveolins, are classically defined as flask-shaped plasma membrane invaginations with a characteristic diameter of 50 to 100 nm. Caveolae/Caveolins play important roles in many physiological and pathological activities. In recent years, Caveolae/Caveolins were found to associate with the absorption, entry, trafficking, replication, assembly and budding for many viruses. This route helps break a new pathway to the exploitation of new antiviral drugs and the prevention and treatment of tumors.

• Authors: Di-Xian Luo, Hui-Ling Yang, Duan-Fang Liao, Yan-Ping Wan
• Journal: Sheng li ke xue jin zhan [Progress in physiology] (Sheng Li Ke Xue Jin Zhan) Vol. 35 Issue 4 Pg. 321-4 (Oct 2004) ISSN: 0559-7765 [Print] China
• PMID: 15727209 (Publication Type: English Abstract, Journal Article, Research Support, Non-U.S. Gov't, Review)

Chemical References

• Caveolins

Topics

• Animals
• Caveolae (physiology)
• Caveolins (physiology)
• Cell Membrane (physiology)
• Endocytosis
• Humans
• Signal Transduction (physiology)
• Simian virus 40 (physiology)
• Virus Diseases (virology)
• Viruses (growth & development)