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Case of neuroleptic malignant-like syndrome precipitated by abrupt fava bean discontinuance.

Abstract
Neuroleptic malignant-like syndrome (NMLS) is well described in the treatment of Parkinson's disease. The syndrome is characterized by fever, rigidity, autonomic instability, elevated creatine phosphokinase levels, and altered level of consciousness, which is usually precipitated by levodopa withdrawal. In recent years, patients have used fava beans to treat Parkinson's symptoms, because the beans contain appreciable amounts of levodopa and have been thought to be a safe adjunctive therapy. We describe a case of NMLS, which was precipitated by the abrupt cessation of fava bean ingestion.
AuthorsShafeeq S Ladha, Russell Walker, Holly A Shill
JournalMovement disorders : official journal of the Movement Disorder Society (Mov Disord) Vol. 20 Issue 5 Pg. 630-1 (May 2005) ISSN: 0885-3185 [Print] United States
PMID15719433 (Publication Type: Case Reports, Journal Article)
CopyrightCopyright 2005 Movement Disorder Society.
Chemical References
  • Levodopa
Topics
  • Diagnosis, Differential
  • Humans
  • Levodopa (adverse effects, analysis)
  • Male
  • Middle Aged
  • Neuroleptic Malignant Syndrome (diagnosis, etiology)
  • Phytotherapy (methods)
  • Substance Withdrawal Syndrome (complications, etiology)
  • Vicia faba (chemistry)

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