HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Nevoid Basal cell carcinoma syndrome with medulloblastoma and meningioma--case report.

Abstract
A 35-year-old man presented with a rare case of nevoid basal cell carcinoma syndrome, or Gorlin's syndrome, associated with both medulloblastoma and meningioma, manifesting as visual field constriction due to multiple parasellar tumors. He had undergone resection of a medulloblastoma at the age of 1 year 9 months, followed by adjunctive irradiation with a total dose of 40 Gy. He presented with multiple subcutaneous nodules on his face and neck. Histological examination of biopsy specimens established the diagnosis of nevoid basal cell carcinoma syndrome. Tuberculum sellae meningioma was removed through a craniotomy, and his symptoms improved. Meningioma is known to occur in the field of therapeutic irradiation, so chemotherapy may be a better option for medulloblastoma associated with nevoid basal cell carcinoma syndrome.
AuthorsYutaka Fukushima, Hidehiro Oka, Satoshi Utsuki, Kazuhisa Iwamoto, Kiyotaka Fujii
JournalNeurologia medico-chirurgica (Neurol Med Chir (Tokyo)) Vol. 44 Issue 12 Pg. 665-8 (Dec 2004) ISSN: 0470-8105 [Print] Japan
PMID15684600 (Publication Type: Case Reports, Journal Article, Review)
Topics
  • Adult
  • Basal Cell Nevus Syndrome (complications)
  • Cerebellar Neoplasms (radiotherapy, surgery)
  • Humans
  • Male
  • Medulloblastoma (radiotherapy, surgery)
  • Meningeal Neoplasms (surgery)
  • Meningioma (surgery)
  • Neoplasms, Second Primary
  • Sella Turcica
  • Vision Disorders (etiology)
  • Visual Fields

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: