The efficacy of three desensitizing agents in treatment of dentine hypersensitivity.

Abstract

PURPOSE:

The purpose of this study was to evaluate the efficacy of three desensitizing agents vs. placebo.

MATERIALS AND METHODS:

One hundred and six hypersensitive teeth of 26 patients were included in this study, and the baseline hypersensitivity level of all teeth was established as 'moderate' by using Visual Analogue Scale (VAS). The teeth were divided into four groups: to the first group 5% potassium nitrate bio-adhesive gel, to the second 2% sodium fluoride bio-adhesive gel and to the third one step adhesive system Prompt L-Pop were applied as desensitizing agents. Group 4 was the control group in which a desensitizer-free bio-adhesive gel was used as placebo. Post treatment and eighth week control measurements were recorded on VAS.

RESULTS:

It was observed that the efficacy of three desensitizing agents did not differ from each other (P >0.05) and except for placebo all reduced moderate dentin hypersensitivity effectively (P <0.05).

CLINICAL RELEVANCE:

Five per cent potassium nitrate, 2% sodium fluoride bio-adhesive gels and one-step bonding agent Prompt L-Pop were effective in reducing moderate dentine hypersensitivity.

• Authors: T Pamir, M Ozyazici, E Baloğlu, B Onal
• Journal: Journal of clinical pharmacy and therapeutics (J Clin Pharm Ther) Vol. 30 Issue 1 Pg. 73-6 (Feb 2005) ISSN: 0269-4727 [Print] England
• PMID: 15659006 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Gels
• Nitrates
• Potassium Compounds
• Prompt L-Pop
• Resin Cements
• Sodium Fluoride
• potassium nitrate

Topics

• Administration, Topical
• Dentin (drug effects)
• Dentin Sensitivity (drug therapy, physiopathology, prevention & control)
• Drug Evaluation, Preclinical (methods)
• Gels (administration & dosage, chemistry, therapeutic use)
• Humans
• Nitrates (administration & dosage, therapeutic use)
• Pain Measurement (drug effects, methods)
• Physical Stimulation (methods)
• Potassium Compounds (administration & dosage, therapeutic use)
• Resin Cements (therapeutic use)
• Sodium Fluoride (administration & dosage, therapeutic use)
• Thermal Conductivity
• Time Factors
• Treatment Outcome