[Botulinum toxin A in the treatment of congenital nystagmus in children].

Abstract

PURPOSE:

To evaluate the use of, botulinum toxin A in the treatment of congenital nystagmus in children.

MATERIAL AND METHODS:

32 children with nystagmus and esotropia (group I), nystagmus and exotropia (group II) and horizontal and vertical nystagmus (group III). Intramuscular injections of botulinum toxin A was performed in all treated children.

RESULTS:

In group I the amplitude of nystagmus diminished of 50%, in group II of 42.9% and in group III of 28,6%. Near and distant visual acuity improved in all treated children.

CONCLUSIONS:

Treatment of congenital nystagmus with botulinum toxin A causes reduction of the amplitude of nystagmus, partial improvement of visual acuity and improvement of anomalous head posture.

• Authors: Ewa Oleszczyńska-Prost
• Journal: Klinika oczna (Klin Oczna) Vol. 106 Issue 4-5 Pg. 625-8 ( 2004) ISSN: 0023-2157 [Print] Poland
• Vernacular Title: Toksyna botulinowa A w leczeniu oczoplasu wrodzonego u dzieci.
• PMID: 15646482 (Publication Type: English Abstract, Journal Article)

Chemical References

• Neuromuscular Agents
• Botulinum Toxins, Type A

Topics

• Botulinum Toxins, Type A (therapeutic use)
• Child
• Child, Preschool
• Drug Administration Schedule
• Esotropia (surgery)
• Humans
• Infant
• Neuromuscular Agents (therapeutic use)
• Nystagmus, Congenital (drug therapy, physiopathology)
• Visual Acuity (physiology)