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Constituents from the stems of Hibiscus taiwanensis.

Abstract
Five new compounds, hibicuslide A (1), hibicuslide B (2), hibicuslide C (3), hibicutaiwanin (4), hibicusin (5), and fifty-one known compounds have been isolated from the stems of Hibiscus taiwanensis. The structures of these compounds were determined by spectroscopic and chemical transformation methods. Among them, mansonone H (19) and uncarinic acid A (30) inhibited HIV replication in H9 lymphocyte cells. The 9,9'-O-feruloyl-(-)-secoisolaricinresinol (12), myriceric acid C (29), and uncarinic acid A (30) showed cytotoxic activity against human lung carcinoma and breast carcinoma.
AuthorsPei-Lin Wu, Tian-Shung Wu, Cai-Xia He, Chia-Hao Su, Kuo-Hsiung Lee
JournalChemical & pharmaceutical bulletin (Chem Pharm Bull (Tokyo)) Vol. 53 Issue 1 Pg. 56-9 (Jan 2005) ISSN: 0009-2363 [Print] Japan
PMID15635230 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Plant Extracts
Topics
  • Cell Line, Tumor
  • HIV-1 (drug effects, physiology)
  • Hibiscus
  • Humans
  • Lymphocytes (drug effects, virology)
  • Plant Extracts (chemistry, isolation & purification, pharmacology)
  • Plant Stems

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