HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[The drug of the month: a new antihypertensive association: Preterax, low doses of ACE inhibitor and thiazide in the same pill].

Abstract
Preterax is the first fixed very- low - dose combination of an angiotensin--converting enzyme inhibitor and a diuretic for first line treatment of hypertension. Its antihypertensive efficacy is remarkable due to the presence of 2 drugs with additional effects. The tolerance is also excellent, with adverse effects similar to placebo. The 24 h blood pressure control is maintained. If necessary, the dose can be doubled (BiPreterax). The medical practitioner must keep in mind that it is an association of perindopril 2 mg and indapamide 0.625 mg with their own contra-indications. These low dose associations are now recommended as one of the 2 options to initiate an antihypertensive drug treatment, with the hope of an improvement in the percentage of well controlled blood pressure in the hypertensive population. Let us remember that the blood pressure target to be reached is at least < 140/90 mmHg. Up till now, no antihypertensive class has demonstrated a superiority over the others. Only the blood pressure fall magnitude is important to prevent cardiovascular complications.
AuthorsJ M Krzesinski
JournalRevue medicale de Liege (Rev Med Liege) Vol. 59 Issue 10 Pg. 601-6 (Oct 2004) ISSN: 0370-629X [Print] Belgium
Vernacular TitleLe medicament du mois : Preterax, la première association fixe faiblement dosée contenant un inhibiteur d'enzyme de conversion et un diurétique thiazide.
PMID15623082 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Drug Combinations
  • indapamide, perindopril drug combination
  • Indapamide
  • Perindopril
Topics
  • Drug Combinations
  • Humans
  • Hypertension (drug therapy)
  • Indapamide (therapeutic use)
  • Perindopril (therapeutic use)
  • Remission Induction
  • Time Factors

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: