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Malignant myoepithelioma of the salivary gland--an untypical clinical course.

Abstract
A case of malignant tumor developing from myoepithelial cells (malignant myoepithelioma) is presented. The primary focus was located in the region of the left submandibular salivary gland. A relapse and metastases were disclosed in the same salivary gland, in the lung and the left breast. Immunohistochemical studies demonstrated positive reactions for S-100 protein, cytokeratins, smooth muscle actin, vimentin, GFAP protein, p53 protein and Ki-67 antigen, and allowed for establishing the final histopathological diagnosis of malignant myoepithelioma.
AuthorsWojciech Rzeszutko, Piotr Kasprzak, Piotr Dziegiel, Marta Rzeszutko, Mirosław Sopel
JournalPolish journal of pathology : official journal of the Polish Society of Pathologists (Pol J Pathol) Vol. 55 Issue 3 Pg. 35-8 ( 2004) ISSN: 1233-9687 [Print] Poland
PMID15619979 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Biomarkers, Tumor
Topics
  • Adult
  • Biomarkers, Tumor (analysis)
  • Breast Neoplasms (secondary, surgery)
  • Female
  • Humans
  • Immunohistochemistry
  • Myoepithelioma (chemistry, secondary, surgery)
  • Neoplasm Recurrence, Local
  • Submandibular Gland Neoplasms (chemistry, pathology, surgery)

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