[Surgery for neutropenic enterocolitis, a complication in acute lymphoblastic leukemia].

Abstract

Neutropenic enterocolitis (NE) is an unusual acute complication of neutropenia, associated with leukemia and lymphoma. It has been observed mainly in the first phase of therapy when drugs are used in maximally tolerated dose. This is a case report of neutropenic enterocolitis in a patient with acute lymphoblast leukemia who received prednisone, vincristine, daunorubicin and L-asparaginase, with perforation of cecal and terminal ileum. Perforation and defect intestine wall was excised and sutured directly in two layers. Protective proximal loop ileostomy was performed at that time.

• Authors: Spasoje Radulović, Zoran Golubović, Branislav Jovanović, Jelena Pejanović
• Journal: Srpski arhiv za celokupno lekarstvo (Srp Arh Celok Lek) Vol. 132 Suppl 1 Pg. 119-21 (Oct 2004) ISSN: 0370-8179 [Print] Serbia
• Vernacular Title: Hirurske komplikacije neutropenijskog enterokolitisa kod akutne limfoblastne leukemija.
• PMID: 15615483 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Antineoplastic Agents

Topics

• Adolescent
• Antineoplastic Agents (adverse effects)
• Enterocolitis, Neutropenic (chemically induced, surgery)
• Female
• Humans
• Precursor Cell Lymphoblastic Leukemia-Lymphoma (drug therapy)