Abstract | OBJECTIVES: DESIGN: In group A (20 patients), the oral lesions were confined to areas in close contact with amalgam fillings. In group B (20 patients), the lesions extended 1 cm beyond the area of contact with amalgam fillings. In group C (20 patients), the oral lesions had no topographic relationship with amalgam fillings. Partial or complete replacement of amalgam fillings was recommended if there was a positive patch test reaction to ammoniated mercury, metallic mercury, or amalgam. Control group D (20 patients) had signs of allergic contact dermatitis. RESULTS: Amalgam fillings were replaced in 13 patients of group A, with significant improvement. Dental amalgam was replaced in 8 patients of group B, with significant improvement. In group C, amalgam replacement in 2 patients resulted in improvement in 1 patient. These results were evaluated after 3 months. No positive patch test reactions to mercury compounds were found in patients with concomitant cutaneous lichen planus and in group D. CONCLUSIONS:
|
Authors | Ronald Laeijendecker, Sybren K Dekker, Piet M Burger, Paul G H Mulder, Theodoor Van Joost, Martino H A Neumann |
Journal | Archives of dermatology
(Arch Dermatol)
Vol. 140
Issue 12
Pg. 1434-8
(Dec 2004)
ISSN: 0003-987X [Print] United States |
PMID | 15611418
(Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article)
|
Chemical References |
|
Topics |
- Adult
- Aged
- Dental Amalgam
(adverse effects, chemistry)
- Device Removal
- Drug Hypersensitivity
(etiology)
- Female
- Humans
- Lichen Planus, Oral
(etiology, pathology, therapy)
- Male
- Mercury
(adverse effects)
- Middle Aged
- Retreatment
- Treatment Outcome
|