Abstract | OBJECT: The appearance of numerous B waves during intracranial pressure (ICP) registration in patients with idiopathic adult hydrocephalus syndrome ( IAHS) is considered to predict good outcome after shunt surgery. The aim of this study was to describe which physical parameters of the cerebrospinal fluid (CSF) system B-waves reflect and to find a method that could replace long-term B-wave analysis. METHODS: Ten patients with IAHS were subjected to long-term registration of ICP and a lumbar constant-pressure infusion test. The B-wave presence, CSF outflow resistance (R(out)), and relative pulse pressure coefficient (RPPC) were assessed using computerized analysis. The RPPC was introduced as a parameter reflecting the joint effect of elastance and pulsatory volume changes on ICP and was determined by relating ICP pulse amplitudes to mean ICP. CONCLUSIONS: The B-wave presence on ICP registration correlates strongly with RPPC (r = 0.91, p < 0.001, 10 patients) but not with CSF R(out). This correlation indicates that B waves-like RPPC-primarily reflect the ability of the CSF system to reallocate and store liquid rather than absorb it. The RPPC-assessing lumbar short-term CSF pulse pressure method could replace the intracranial long-term B-wave analysis.
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Authors | Niklas Lenfeldt, Nina Andersson, Aina Agren-Wilsson, A Tommy Bergenheim, Lars-Owe D Koskinen, Anders Eklund, Jan Malm |
Journal | Journal of neurosurgery
(J Neurosurg)
Vol. 101
Issue 6
Pg. 944-50
(Dec 2004)
ISSN: 0022-3085 [Print] United States |
PMID | 15597755
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Adult
- Blood Pressure
- Cerebrospinal Fluid
- Elasticity
- Humans
- Hydrocephalus, Normal Pressure
(diagnosis, physiopathology)
- Intracranial Pressure
- Linear Models
- Models, Biological
- Monitoring, Physiologic
(methods)
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