Outcomes after pylorus-preserving gastrectomy for early gastric cancer: a prospective multicenter trial.

• Abstract: The aim of the present study was to compare in a prospective, multicenter trial the results early and late after pylorus-preserving gastrectomy (PPG) versus conventional distal gastrectomy (CDG) with Billroth I anastomosis for early gastric cancer. Eighty-one patients with early gastric cancer were randomized and then underwent either PPG or CDG. Duration of operation, intraoperative blood loss, days until removal of the nasogastric tube, days until start of oral intake, and decrease in body weight were studied as parameters for outcomes early after the surgery. Late results were studied in patients followed for longer than 3 years. Change in body weight, status of oral intake, symptoms suggesting early dumping syndrome, and overall satisfaction were addressed in the questionnaire. The presence of gallstones was examined with ultrasonography. There were no differences in early results between PPG and CDG. The incidence of early dumping syndrome was lower in PPG (8%) than in CDG (33%). Other late results including the incidence of gallstones were not different between the 2 groups. These results indicate that PPG is as safe as CDG and has an advantage in terms of early dumping syndrome.
• Authors: Chikashi Shibata, Ken-ichí Shiiba, Yuji Funayama, Seiichi Ishii, Kouhei Fukushima, Takayuki Mizoi, Kaori Koyama, Koh Miura, Seiki Matsuno, Hiroo Naito, Eiichi Kato, Tsuyohiko Honda, Satoshi Momono, Akio Ouchi, Yoshikazu Ashino, Yoshinobu Takahashi, Tsuneaki Fujiya, Akihiro Iwatsuki, Iwao Sasaki (Affiliation: Department of Surgery, Tohoku University School of Medicine, Seiryo-machi, 980-8574 Aoba-ku, Sendai, Japan. cshibata at gonryo.med.tohoku.ac.jp)
• Journal: World journal of surgery (World J Surg) Vol. 28 Issue 9 Pg. 857-61 (Sep 2004) ISSN: 0364-2313 [Print] United States
• PMID: 15593456 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Multicenter Study, Randomized Controlled Trial)

Topics

• Female
• Gastrectomy (methods)
• Humans
• Male
• Middle Aged
• Prospective Studies
• Pylorus
• Stomach Neoplasms (pathology, surgery)
• Time Factors
• Treatment Outcome