Abstract | OBJECTIVE: METHODS: Clinical and laboratory findings, and perinatal-neonatal outcomes of all pregnants with severe preeclampsia, eclampsia and HELLP have been prospectively recorded. Results were compared by means of Student's t test, chi2 analysis and Fisher's exact test as appropriate. RESULTS: Among 367 consecutive severe preeclampsia, 106 (29%) had HELLP syndrome, 261 (71%) had severe preeclampsia and eclampsia. Mean gestational age and birth weight at delivery in severe preeclampsia without HELLP syndrome and in HELLP syndrome were 34.1 +/- 6.1 vs. 33.0 +/- 5.8 weeks (p = 0.119) and 1,886 +/- 764 vs. 1,724 +/- 776 g (p = 0.063), respectively. Comparing overall fetal mortality (4.6 vs. 10.3%, p = 0.009) and perinatal mortality (8.0% vs. 16.8%, p = 0.026) in severe preeclampsia- eclampsia and HELLP syndrome, respectively, there were statistically significant differences. But when analyses were performed according to gestational age before and after 32nd gestational week, the difference of perinatal mortality between the two groups was non-significant (p = 0.644 and p = 0.250), suggesting borderline difference. The most common contributing factor for fetal death after 32nd week was due to abruptio placenta without prenatal follow-up. Neonatal morbidity and neonatal mortality (4.8 vs. 6.3%, p = 0.905) in severe preeclampsia- eclampsia and HELLP syndrome respectively were similar and the difference was statistically nonsignificant. CONCLUSIONS:
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Authors | Ahmet Gul, Altan Cebeci, Halil Aslan, Ibrahim Polat, Aykut Ozdemir, Yavuz Ceylan |
Journal | Gynecologic and obstetric investigation
(Gynecol Obstet Invest)
Vol. 59
Issue 2
Pg. 113-8
( 2005)
ISSN: 0378-7346 [Print] Switzerland |
PMID | 15591806
(Publication Type: Comparative Study, Journal Article)
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Copyright | Copyright 2005 S. Karger AG, Basel. |
Topics |
- Adult
- Eclampsia
(complications)
- Female
- Fetal Mortality
- Gestational Age
- HELLP Syndrome
(complications)
- Humans
- Infant Mortality
- Infant, Newborn
- Pre-Eclampsia
(complications)
- Pregnancy
- Pregnancy Outcome
- Prospective Studies
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