Abstract |
Plants and microorganisms are the treasury of bioactive metabolites including useful chemical ligands. Chemical ligands that induce beta-cell differentiation may be useful as new therapeutic agents for both type-1 and type-2 diabetes mellitus. We isolated conophylline from the leaves of Ervatamia microphylla as an agent that induce insulin production in rat pancreatic acinar carcinoma cells.
|
Authors | Hiroshi Takatsuna, Kazuo Umezawa |
Journal | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
(Biomed Pharmacother)
Vol. 58
Issue 10
Pg. 610-3
(Dec 2004)
ISSN: 0753-3322 [Print] France |
PMID | 15589071
(Publication Type: Journal Article, Review)
|
Topics |
- Animals
- Drug Evaluation, Preclinical
(methods)
- Humans
- Pancreas
(cytology, drug effects, physiology)
- Regeneration
(drug effects, physiology)
|