Abstract | BACKGROUND: OBJECTIVE: This study investigated (1) the correlation and clinical relevance of positive patch-test reactions to CAPB and AA in cases of ACD and (2) the rate of positive reactions to CDEA and formaldehyde in these patients. METHODS: Patients with patch-test reactions to either CAPB or AA during 2001 were retrospectively identified. Relevance of reactions to CAPB and AA was then graded as definite, probable, or not relevant, based on patient follow-up. The proportion of these patients who also had positive reactions to CDEA or formaldehyde was noted. RESULTS: Of 957 patch-tested patients, 49 had positive reactions to either CAPB (42.9%) or AA (34.3%) or to both (22.8%). Of these patients, 35 were available for follow-up. Twenty-nine (83.0%) of these patients identified the surfactant in their home products. In all of these patients, the dermatitis was felt to be due in whole or in part to CAPB exposure. Two patients (5.7%) had a positive reaction to CDEA, and 8 patients (23%) had a positive reaction to formaldehyde. CONCLUSION: Patch testing with both CAPB and AA identifies patients with ACD relevant to exposure to CAPB. Since few patients react to both allergens, testing with both separately is useful. Formaldehyde allergy was overrepresented in CAPB-allergic patients in this series of patients.
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Authors | Nicole L Brey, Joseph F Fowler Jr |
Journal | Dermatitis : contact, atopic, occupational, drug
(Dermatitis)
Vol. 15
Issue 1
Pg. 7-9
(Mar 2004)
ISSN: 1710-3568 [Print] United States |
PMID | 15573642
(Publication Type: Evaluation Study, Journal Article)
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Chemical References |
- Allergens
- Amines
- Surface-Active Agents
- Formaldehyde
- Betaine
- cocamidopropyl betaine
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Topics |
- Allergens
(adverse effects)
- Amines
(adverse effects)
- Betaine
(adverse effects, analogs & derivatives)
- Cross Reactions
- Dermatitis, Allergic Contact
(diagnosis)
- Formaldehyde
(adverse effects)
- Humans
- Patch Tests
(standards)
- Predictive Value of Tests
- Surface-Active Agents
(adverse effects)
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