Asymptomatic massive dural ectasia associated with neurofibromatosis type 1 threatening spinal column support: treatment by anterior vascularized fibula graft.

We report the case of a girl with a dystrophic neurofibromatosis lumbar scoliosis with asymptomatic progression and spread of dystrophic characteristics over 18 years. Resorption of almost the entire anterior column of L1-L4 had occurred despite a previous posterior instrumentation and fusion. A vascularized fibula bone graft wrapped in titanium mesh was used as an anterior structural graft. With close follow-up, the need for this type of salvage surgery might have been averted. Further follow-up showed no graft resorption and unchanged sagittal alignment after 3 years.
AuthorsM de Kleuver, J P W van Jonbergen, D D Langeloo
JournalJournal of spinal disorders & techniques (J Spinal Disord Tech) Vol. 17 Issue 6 Pg. 539-42 (Dec 2004) ISSN: 1536-0652 [Print] United States
PMID15570129 (Publication Type: Case Reports, Journal Article)
  • Adolescent
  • Dilatation, Pathologic (etiology, surgery)
  • Disease Progression
  • Dura Mater (abnormalities, pathology, surgery)
  • Female
  • Fibula (transplantation)
  • Humans
  • Lumbar Vertebrae
  • Neurofibromatosis 1 (complications)
  • Scoliosis (complications, surgery)
  • Treatment Outcome

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!

Choose Username:
Verify Password: