[The levels of T lymphocytes and thymic peptide antibodies in patients with infiltrative pulmonary tuberculosis and in those with cancer diseases].

Abstract

A relationship of the levels of thymic peptide antibodies to those of the population and subpopulations of T lymphocytes was studied in patients with pulmonary tuberculosis, lung or breast cancer. Indirect immunofluorescence was used to determine the count of CD3-, CD4-, CD80, CD38-, CD25-, CD71-, and CD95-lymphocytes. The levels of thymic peptide antibodies were estimated by enzyme immunoassay. Unlike cancer diseases, pulmonary tuberculosis was characterized by the combination of a significantly inverse correlation between the relative count of CD3-, CD4-, CD8-lymphocytes the levels of thymogen antibodies with a significantly direct correlation between the absolute count of CD25- and CD38-lymphocytes. The studies may recommend that the levels of thymic peptide antigens should be determined to select persons with immunodeficiency particularly those with inflammatory diseases.

• Authors: A I Autenshlius, Iu V Sedova, A N Shkunov, E S Mikhaĭlova, N B Kuznetsova, K G Rakhmanov
• Journal: Problemy tuberkuleza i boleznei legkikh (Probl Tuberk Bolezn Legk) Issue 10 Pg. 31-4 ( 2004) ISSN: 1728-2993 [Print] Russia (Federation)
• Vernacular Title: Soderzhanie T-limfotsitov i urovni antitel k peptidam timusa u bol'nykh infiltrativnym tuberkulezom legkikh i u bol'nykh s onkologicheskimi zabolevaniiami.
• PMID: 15568317 (Publication Type: Journal Article)

Chemical References

• Antibodies, Bacterial
• CD3 Complex
• CD4 Antigens
• Receptors, Antigen, T-Cell

Topics

• Antibodies, Bacterial (immunology)
• CD3 Complex (immunology)
• CD4 Antigens (immunology)
• CD8-Positive T-Lymphocytes (immunology)
• Female
• Humans
• Lung Neoplasms (immunology)
• Male
• Receptors, Antigen, T-Cell (immunology)
• T-Lymphocytes (immunology)
• Tuberculosis, Pulmonary (immunology)