[Topical application of morphine gel in inflammatory mucosal and cutaneous lesions].

Abstract

AIM:

The aim of this study was to demonstrate a peripheral local opioid effect using case examples involving inflammatory mucosal and cutaneous lesions.

METHODS:

A 0.1% morphine gel, mixed in the hospital pharmacy, was applied several times daily to inflammatory mucosal lesions (oral, anogenital and in one patient to a skin ulcer). The effects and side effects were documented.

RESULT:

All patients experienced a significant reduction in pain with the use of topical morphine gel and no side effects were seen.

CONCLUSION:

Topical peripheral application of morphine gel is a simple, effective method that can be carried out by patients several times a day with few side effects.

• Authors: M Platzer, R Likar, C Stein, E Beubler, R Sittl
• Journal: Schmerz (Berlin, Germany) (Schmerz) Vol. 19 Issue 4 Pg. 296-301 (Aug 2005) ISSN: 0932-433X [Print] Germany
• Vernacular Title: Topische Applikation von Morphingel bei entzündlichen Haut- und Schleimhautläsionen.
• PMID: 15568159 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Analgesics, Opioid
• Morphine

Topics

• Administration, Topical
• Adult
• Aged
• Analgesics, Opioid (administration & dosage, therapeutic use)
• Female
• Humans
• Intestinal Mucosa (drug effects, pathology)
• Male
• Middle Aged
• Morphine (administration & dosage, therapeutic use)
• Mucous Membrane (drug effects, pathology)
• Skin Diseases (physiopathology)
• Skin Ulcer (physiopathology)