Abstract | STUDY OBJECTIVE: DESIGN: Prospective case control study (Canadian Task Force classification II-2). SETTING: University teaching hospital. PATIENTS: Eighty-four healthy premenopausal women with symptomatic uterine myoma(s) undergoing UAE or hysterectomy. INTERVENTION: MEASUREMENTS AND MAIN RESULTS: The main outcome was the differences in serum FSH, LH, E2, and ultrasound findings before and after UAE or hysterectomy. Of the 68 patients who underwent UAE and 16 who underwent hysterectomy, 48 and 13 respectively, completed 6-month follow-up. The mean age of the patients in the UAE group was 44.9 +/- 3.8 years and 43.7 +/- 5.6 years in the hysterectomy group. There was no significant difference in serum FSH before (8.9 +/- 0.7 IU/L) and 6 months after UAE (9.9 +/- 1.0 lU/L), and between the baseline (10.4 +/- 1.8 lU/L) and 6 months posthysterectomy (7.8 +/- 1.8 lU/L). The uterine volume 6 months after UAE (361 +/- 50 mL) was significantly smaller than before UAE(538 +/- 38mL; p =.005, 95% CI 44-241). Compared with baseline (154 +/- 20 mL), the dominant myoma volume was smaller at 6 months after UAE (97 +/- 16 mL; p <.05, 95% CI 1.57-62). CONCLUSION:
|
Authors | Sarah Healey, Karen Buzaglo, Laurent Seti, David Valenti, Togas Tulandi |
Journal | The Journal of the American Association of Gynecologic Laparoscopists
(J Am Assoc Gynecol Laparosc)
Vol. 11
Issue 3
Pg. 348-52
(Aug 2004)
ISSN: 1074-3804 [Print] United States |
PMID | 15559347
(Publication Type: Comparative Study, Journal Article)
|
Chemical References |
- Estradiol
- Luteinizing Hormone
- Follicle Stimulating Hormone
|
Topics |
- Adult
- Case-Control Studies
- Embolization, Therapeutic
- Estradiol
(blood)
- Female
- Follicle Stimulating Hormone
(blood)
- Humans
- Hysterectomy
- Leiomyoma
(surgery)
- Luteinizing Hormone
(blood)
- Middle Aged
- Treatment Outcome
- Uterine Neoplasms
(surgery)
- Uterus
(blood supply)
|