Supracubital perineurioma misdiagnosed as carpal tunnel syndrome: case report.

Abstract

BACKGROUND:

Perineuriomas have been defined as tumorous lesions of the peripheral nerves which derive from perineurial cell proliferation and may be associated with abnormalities on chromosome 22.

CASE PRESENTATION:

Three years after a painful cubital vein procaine injection, a 33 year-old man developed a median nerve lesion, initially diagnosed as carpal tunnel syndrome. Symptoms progressed despite appropriate surgery. Clinical and electrophysiological re-evaluation revealed a fusiform mass at the distal upper arm, confirmed by MRI. Immunohistochemical studies classified the tumor as a mixed perineurioma and neuroma.

CONCLUSIONS:

Perineurioma mixed with neuroma may potentially caused by the previous trauma or cytotoxic effects of procaine.

• Authors: Carsten Saft, Juergen E Andrich, Eva Neuen-Jacob, Gebhard Schmid, Ludger Schols, Georgios Amoiridis
• Journal: BMC neurology (BMC Neurol) Vol. 4 Issue 1 Pg. 19 (Nov 21 2004) ISSN: 1471-2377 [Electronic] England
• PMID: 15555068 (Publication Type: Case Reports, Journal Article)

Chemical References

• Procaine

Topics

• Adult
• Carpal Tunnel Syndrome (diagnosis)
• Diagnosis, Differential
• Humans
• Magnetic Resonance Imaging
• Male
• Median Nerve (injuries, pathology, surgery)
• Nerve Sheath Neoplasms (diagnosis, etiology, surgery)
• Pain (etiology)
• Procaine (adverse effects)
• Sural Nerve (transplantation)