[New aspects in uv and photochemotherapy].

Abstract

Recent data show that from a pharmacological point of view topical (cream or bath) PUVA therapy is superior to systemic PUVA. Due to a significant reduction of side effects compared to systemic PUVA, bath PUVA has now started to replace oral PUVA therapy. Narrowband UVB has proved to be superior to broadband UVB in the treatment of psoriasis and is effective for a number of dermatoses such as vitilgo, atopic dermatitis and polymorphic light eruption. UVA1 phototherapy is highly effective in the treatment of moderate to severe atopic dermatitis and sclerosing diseases of the skin. Data dealing with UVA1 phototherapy for other indications are still preliminary. High-dose UVA1 is has been widely replaced by medium-dose UVA1, as a number of studies have shown similar therapeutic efficacy of both dose regimens.

• Authors: M Grundmann-Kollman, A Tanew
• Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete (Hautarzt) Vol. 55 Issue 12 Pg. 1159-66; quiz 1167 (Dec 2004) ISSN: 0017-8470 [Print] Germany
• Vernacular Title: Neuere Aspekte in der UV- und Photochemotherapie.
• PMID: 15549209 (Publication Type: English Abstract, Journal Article, Review)

Topics

• Humans
• PUVA Therapy (methods, trends)
• Photochemotherapy (methods, trends)
• Practice Guidelines as Topic
• Practice Patterns, Physicians' (trends)
• Skin Diseases (drug therapy)
• Treatment Outcome