| Abstract | We randomised 119 patients who had been referred for removal of partially impacted mandibular third molars to be given either metronidazole 1600 mg or placebo as a single dose 45 min before operation. Ten of the fifty-nine patients who were given metronidazole and 13 of the 60 given placebo developed dry sockets. Two variables were significantly associated with the development of a dry socket: pericoronitis and oral contraceptives. |
| Authors | M Bergdahl, L Hedström
(Affiliation: Department of Odontology, Faculty of Medicine and Odontology, Umeå University, Umeå, Sweden.)
|
| Journal | The British journal of oral & maxillofacial surgery
(Br J Oral Maxillofac Surg)
Vol. 42
Issue 6
Pg. 555-8
(Dec 2004)
ISSN: 0266-4356 Scotland |
| PMID | 15544888
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
|
| Chemical References |
- Anti-Infective Agents
- Contraceptives, Oral
- Metronidazole
|
| Topics |
- Administration, Oral
- Adolescent
- Adult
- Anti-Infective Agents
(administration & dosage)
- Chi-Square Distribution
- Contraceptives, Oral
(adverse effects)
- Double-Blind Method
- Dry Socket
(etiology, prevention & control)
- Female
- Humans
- Logistic Models
- Male
- Mandible
- Metronidazole
(administration & dosage)
- Molar, Third
(surgery)
- Pericoronitis
(complications)
- Preoperative Care
- Statistics, Nonparametric
- Tooth Extraction
(adverse effects)
- Tooth, Impacted
(complications, surgery)
|