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Thyroid metastasis from renal cell carcinoma eight years after radical nephrectomy: a case report.

AbstractA forty-five-year-old female patient presented with thyroid nodules eight years after radical nephrectomy for renal cell carcinoma (T2N0M0, grade 2, clear cell subtype) in the right kidney. Ultrasonography of the neck showed multiple hypoechoic macronodules. There was no lymphadenomegaly. During total thyroidectomy following an initial diagnosis of multinodular goiter, frozen section analysis was made, which showed metastasis from renal cell carcinoma. Immunohistochemical studies demonstrated that the tumor cells were negative for thyroglobulin staining. No recurrences or other metastatic disease were seen during a follow-up period of 12 months. Although clinically the thyroid gland is a rare site for tumor metastasis, this possibility should be kept in mind in patients with a previous history of renal cell carcinoma.
AuthorsCanan Uzel, Halil Coşkun, Tarik Terzioğlu, Necdet Aras (Affiliation: Department of General Surgery, VKV American Hospital, Istanbul, Turkey. cananuzel at hotmail.com)
JournalKulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat (Kulak Burun Bogaz Ihtis Derg) Vol. 11 Issue 5 Pg. 152-6 (Nov 2003) ISSN: 1300-7475 Turkey
PMID15542944 (Publication Type: Case Reports, Journal Article)
Topics
  • Carcinoma, Renal Cell (secondary, surgery)
  • Diagnosis, Differential
  • Female
  • Humans
  • Kidney Neoplasms (pathology, surgery)
  • Middle Aged
  • Neoplasm Metastasis
  • Neoplasm Staging
  • Thyroid Neoplasms (diagnosis, secondary, surgery)
  • Thyroidectomy