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Fulminant hepatic failure related to omeprazole.

Abstract
Omeprazole is a new hydrogen-potassium adenosine triphosphatase antagonist with indications for severe reflux esophagitis and Zollinger-Ellison syndrome. Side effects involving the liver have consisted of minimal elevations of hepatocellular enzymes with higher dosages. We present what we believe is the first reported case of fulminant hepatic failure related to omeprazole.
AuthorsV Jochem, R Kirkpatrick, J Greenson, M Brogan, T Sturgis, C Cook-Glenn
JournalThe American journal of gastroenterology (Am J Gastroenterol) Vol. 87 Issue 4 Pg. 523-5 (Apr 1992) ISSN: 0002-9270 [Print] United States
PMID1553942 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Omeprazole
Topics
  • Esophagitis, Peptic (drug therapy)
  • Hepatic Encephalopathy (chemically induced)
  • Humans
  • Male
  • Middle Aged
  • Omeprazole (adverse effects)

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