HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Diagnosis of palpable breast masses: ultrasound-guided large core biopsy in a multidisciplinary setting.

Abstract
Cytologic diagnosis of palpable breast masses is an accepted method for diagnosis. However, the high nondiagnostic rate causes repeat biopsy, unnecessary delays, and increased costs. Our purpose is to evaluate the use of ultrasound (US)-guided large-core needle biopsy as part of the minimally invasive multidisciplinary diagnosis of palpable breast masses. We studied 502 consecutive patients with 510 palpable solid breast masses seen and evaluated by a multidisciplinary team. Patients had US-guided core biopsy. Clinical-imaging-pathologic correlation (CIPC) was done in all cases. Core biopsy was deemed conclusive if CIPC was congruent and was used to guide definitive management. The median age of our patients was 39 years. Median tumor size was 2.2 cm. Of these cases, 463 (91%) had a conclusive diagnosis on CIPC. Core needle findings on 47 masses were nondefinitive to guide therapy (fibroepithelial lesion, atypical ductal hyperplasia, intraductal papilloma, CIPC). Three cancers were detected in this group on excisional biopsy. In conclusion, US-guided large-core needle biopsy is a sensitive method for diagnosis of palpable breast masses. Multidisciplinary correlation of clinical findings, imaging, and pathology is essential for success. This approach improves use of operating room resources and maximizes patient participation in the decision-making process.
AuthorsHernan I Vargas, M Perla Vargas, Katherine D Gonzalez, Rose Venegas, Martha Canet, Melissa Burla, Kamal Eldrageely, Iraj Khalkhali
JournalThe American surgeon (Am Surg) Vol. 70 Issue 10 Pg. 867-71 (Oct 2004) ISSN: 0003-1348 [Print] United States
PMID15529839 (Publication Type: Journal Article)
Topics
  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Biopsy, Needle (methods)
  • Breast (pathology)
  • Breast Neoplasms (diagnostic imaging, pathology)
  • Cross-Sectional Studies
  • Female
  • Humans
  • Middle Aged
  • Patient Care Team
  • Predictive Value of Tests
  • Sensitivity and Specificity
  • Treatment Outcome
  • Ultrasonography, Interventional (methods)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: