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[Features of the treatment of heart failure in the elderly].

Abstract
PHARMACOLOGICAL MODIFICATIONS TO BE TAKEN INTO ACCOUNT: In elderly patients, there is a modification in the distribution columns of drugs, an alteration in glomerular filtration (doses require adaptation) and tubular function (greater sensitivity to low salt diet and diuretics), and a reduction in the hepatic elimination capacity. FOR SYSTOLIC HEART FAILURE: The choice of drugs is in practice the same as that for younger patients: diuretics, antialdosterone agents, converting enzyme inhibitors, angiotensin II receptor antagonists, beta-blockers and digitalics. FOR DIASTOLIC HEART FAILURE: The therapeutic approach combines an etiologic treatment (blood pressure, myocardial ischaemia), prevention and the rapid treatment of the decompensation factors (atrial arrhythmia), a pharmacological treatment (converting enzyme inhibitors, angiotensin II receptor antagonists, and bradycardia lowering agents). Non-pharmacological measures include dietary restrictions, regular physical exercise, and education for the patient and the family.
AuthorsJean-François Aupetit, Katayoun Bourdariat, Michel Lestaevel
JournalPresse medicale (Paris, France : 1983) (Presse Med) Vol. 33 Issue 16 Pg. 1086-8 (Sep 25 2004) ISSN: 0755-4982 [Print] France
Vernacular TitleParticularités du traitement de l'insuffisance cardiaque du sujet âgé.
PMID15523262 (Publication Type: English Abstract, Journal Article, Review)
Chemical References
  • Adrenergic beta-Antagonists
  • Angiotensin-Converting Enzyme Inhibitors
  • Diuretics
  • Mineralocorticoid Receptor Antagonists
Topics
  • Adrenergic beta-Antagonists (therapeutic use)
  • Aged
  • Aging
  • Angiotensin-Converting Enzyme Inhibitors (therapeutic use)
  • Diet
  • Diuretics (therapeutic use)
  • Exercise Therapy
  • Glomerular Filtration Rate
  • Heart Failure (drug therapy, pathology)
  • Humans
  • Hypertension (complications)
  • Liver (physiology)
  • Mineralocorticoid Receptor Antagonists (therapeutic use)
  • Myocardial Ischemia (complications)
  • Risk Factors

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