Abstract |
PHARMACOLOGICAL MODIFICATIONS TO BE TAKEN INTO ACCOUNT: In elderly patients, there is a modification in the distribution columns of drugs, an alteration in glomerular filtration (doses require adaptation) and tubular function (greater sensitivity to low salt diet and diuretics), and a reduction in the hepatic elimination capacity. FOR SYSTOLIC HEART FAILURE: The choice of drugs is in practice the same as that for younger patients: diuretics, antialdosterone agents, converting enzyme inhibitors, angiotensin II receptor antagonists, beta-blockers and digitalics. FOR DIASTOLIC HEART FAILURE: The therapeutic approach combines an etiologic treatment (blood pressure, myocardial ischaemia), prevention and the rapid treatment of the decompensation factors (atrial arrhythmia), a pharmacological treatment (converting enzyme inhibitors, angiotensin II receptor antagonists, and bradycardia lowering agents). Non-pharmacological measures include dietary restrictions, regular physical exercise, and education for the patient and the family.
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Authors | Jean-François Aupetit, Katayoun Bourdariat, Michel Lestaevel |
Journal | Presse medicale (Paris, France : 1983)
(Presse Med)
Vol. 33
Issue 16
Pg. 1086-8
(Sep 25 2004)
ISSN: 0755-4982 [Print] France |
Vernacular Title | Particularités du traitement de l'insuffisance cardiaque du sujet âgé. |
PMID | 15523262
(Publication Type: English Abstract, Journal Article, Review)
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Chemical References |
- Adrenergic beta-Antagonists
- Angiotensin-Converting Enzyme Inhibitors
- Diuretics
- Mineralocorticoid Receptor Antagonists
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Topics |
- Adrenergic beta-Antagonists
(therapeutic use)
- Aged
- Aging
- Angiotensin-Converting Enzyme Inhibitors
(therapeutic use)
- Diet
- Diuretics
(therapeutic use)
- Exercise Therapy
- Glomerular Filtration Rate
- Heart Failure
(drug therapy, pathology)
- Humans
- Hypertension
(complications)
- Liver
(physiology)
- Mineralocorticoid Receptor Antagonists
(therapeutic use)
- Myocardial Ischemia
(complications)
- Risk Factors
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