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Usefulness of pindolol for treatment of neurocardiogenic syncope.

Abstract
This study evaluated the efficacy of pindolol, a noncardioselective beta blocker with intrinsic sympathetic activity, on neurocardiogenic syncope using a head-up tilt-table test in 66 patients. Pindolol was equally effective in men and women and the 2 age groups (>60 and <60 years) of the study cohort. The earliest benefit was seen </=3 days after initiating treatment. Side effects were better tolerated in younger patients (age <60 years).
AuthorsNandini Nair, Farooq A Padder, Steven P Kutalek, Bharat K Kantharia
JournalThe American journal of cardiology (Am J Cardiol) Vol. 94 Issue 9 Pg. 1189-91 (Nov 01 2004) ISSN: 0002-9149 [Print] United States
PMID15518620 (Publication Type: Comparative Study, Journal Article)
Chemical References
  • Adrenergic beta-Antagonists
  • Pindolol
Topics
  • Adolescent
  • Adrenergic beta-Antagonists (therapeutic use)
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Blood Pressure (drug effects)
  • Drug Evaluation
  • Female
  • Follow-Up Studies
  • Heart Rate (drug effects)
  • Humans
  • Male
  • Middle Aged
  • Pindolol (therapeutic use)
  • Syncope, Vasovagal (drug therapy)
  • Tilt-Table Test
  • Treatment Outcome

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