[Panzytopenia from combination therapy with azathioprin and allopurinol].

Abstract

Azathioprine has been used in rheumatology for more than twenty years. Indications are collagen diseases with multiorgan involvement, where co-medications are frequently necessary. We describe a patient suffering from pancytopenia following a combination therapy of azathioprine and allopurinol because of lupus erythematodes and diabetic nephropathy with hyperuricemia.

• Authors: W Seidel
• Journal: Zeitschrift fur Rheumatologie (Z Rheumatol) Vol. 63 Issue 5 Pg. 425-7 (Oct 2004) ISSN: 0340-1855 [Print] Germany
• Vernacular Title: Panzytopenie unter kombinierter Behandlung mit Azathioprin und Allopurinol.
• PMID: 15517303 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Antirheumatic Agents
• Autoantibodies
• Gout Suppressants
• Allopurinol
• Azathioprine

Topics

• Aged
• Allopurinol (adverse effects, therapeutic use)
• Antirheumatic Agents (adverse effects, therapeutic use)
• Autoantibodies (blood)
• Azathioprine (adverse effects, therapeutic use)
• Blood Cell Count
• Diabetes Mellitus, Type 2 (blood, drug therapy)
• Diabetic Nephropathies (drug therapy, immunology)
• Dose-Response Relationship, Drug
• Drug Interactions
• Drug Monitoring
• Drug Therapy, Combination
• Erythrocyte Count
• Female
• Gout Suppressants (adverse effects, therapeutic use)
• Hematopoiesis (drug effects)
• Humans
• Hyperuricemia (drug therapy, immunology)
• Lupus Erythematosus, Systemic (drug therapy, immunology)
• Pancytopenia (chemically induced, diagnosis, immunology)