Chemotherapy for ovarian mucinous cystadenocarcinoma during pregnancy: a case report.

Abstract

There is limited experience in the treatment of epithelial ovarian malignancy with chemotherapy during pregnancy. We present the case of a 36-year-old women with ovarian mucinous cystadenocarcinoma during pregnancy, on whom exploratory laparotomy was performed at the gestational age of 16 weeks. Afterwards chemotherapy with cyclophosphamide (500 mg/m2) and cisplatin (50 mg/m2) was administered beginning at the second trimester of pregnancy due to surgical Stage Ic. Although preterm labor and a prematurely ruptured membrane occurred at the gestational age of 29 weeks before the fourth course of chemotherapy, there was still a satisfactory outcome for mother and fetus after an emergency cesarean section due to breech presentation at the gestational age of 30 weeks.

• Authors: H-P Huang, C-N Fang, Y-Y Kan
• Journal: European journal of gynaecological oncology (Eur J Gynaecol Oncol) Vol. 25 Issue 5 Pg. 635-6 ( 2004) ISSN: 0392-2936 [Print] Singapore
• PMID: 15493185 (Publication Type: Case Reports, Journal Article)

Chemical References

• Cyclophosphamide
• Cisplatin

Topics

• Adult
• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Cesarean Section
• Cisplatin (administration & dosage)
• Cyclophosphamide (administration & dosage)
• Cystadenocarcinoma, Mucinous (diagnosis, drug therapy, pathology)
• Diagnosis, Differential
• Female
• Humans
• Ovarian Neoplasms (diagnosis, drug therapy, pathology)
• Pregnancy
• Pregnancy Complications, Neoplastic (diagnosis, drug therapy, pathology)
• Pregnancy Trimester, Second