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Plasmapheresis in the treatment of hyperthyroidism associated with agranulocytosis: A case report.

Abstract
Plasmapheresis, also known as therapeutic plasma exchange, is used in the treatment of several disorders. Temporary improvement after plasmapheresis in cases with thyrotoxicosis has been reported. A 55-year-old woman presented with agranulocytosis induced by propylthiouracil and clinical signs of heart failure. Three sessions of plasmapheresis were performed. We observed an improvement of thyroid hormone levels and clinical findings as well. Plasmapheresis can be an option when drug treatment of thyrotoxicosis fails.
AuthorsBirol Guvenc, Cagatay Unsal, Emel Gurkan, Süleyman Dincer
JournalJournal of clinical apheresis (J Clin Apher) Vol. 19 Issue 3 Pg. 148-50 ( 2004) ISSN: 0733-2459 [Print] United States
PMID15493048 (Publication Type: Case Reports, Journal Article)
Copyright(c) 2004 Wiley-Liss, Inc.
Chemical References
  • Antithyroid Agents
  • Propylthiouracil
Topics
  • Agranulocytosis (chemically induced)
  • Antithyroid Agents (adverse effects)
  • Female
  • Humans
  • Hyperthyroidism (therapy)
  • Middle Aged
  • Plasmapheresis
  • Propylthiouracil (adverse effects)

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