Burning mouth syndrome: the efficacy of lipoic acid on subgroups.

Abstract

OBJECTIVE:

We have examined the effect of alpha-lipoic acid (ALA, tioctic acid; Tiobec), a free radical scavenger, on the discomfort of burning mouth syndrome (BMS) in patients who had used tranquillizers previously, compared with those who had not.

METHODS:

In this study we gave lipoic acid for 2 months to two groups of 20 BMS patients, one of which had previously been treated with tranquillizers.

RESULTS:

The results showed greater effectiveness of lipoic acid in BMS patients who had not previously used tranquillizers.

CONCLUSIONS:

The patients with BMS who had previously been treated with tranquillizers responded poorly to therapy with lipoic acid compared with those who had not received previous psychotropic therapy.

• Authors: F Femiano, F Gombos, C Scully
• Journal: Journal of the European Academy of Dermatology and Venereology : JEADV (J Eur Acad Dermatol Venereol) Vol. 18 Issue 6 Pg. 676-8 (Nov 2004) ISSN: 0926-9959 [Print] England
• PMID: 15482293 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Antioxidants
• Tranquilizing Agents
• Thioctic Acid

Topics

• Adult
• Aged
• Antioxidants (therapeutic use)
• Burning Mouth Syndrome (drug therapy)
• Chi-Square Distribution
• Female
• Humans
• Male
• Middle Aged
• Thioctic Acid (therapeutic use)
• Tranquilizing Agents (therapeutic use)
• Treatment Outcome