| Abstract | The primary pathology of Parkinson's disease is the degeneration of dopaminergic neurons in the nigrostriatal pathway, resulting in a significant reduction in striatum dopamine concentration which is responsible for the altered motor functions. With time and disease progression, efficacy of dopaminergic therapy becomes unpromising. We herein review the recent advance of treatment of Parkinson's disease to prevent ongoing progressive nature of Parkinson's disease. |
| Authors | Etsuro Matsubara
(Affiliation: Department of Neurology, Graduate School of Medicine and Dentistry, Okayama University.)
|
| Journal | Nippon rinsho. Japanese journal of clinical medicine
(Nippon Rinsho)
Vol. 62
Issue 9
Pg. 1725-8
(Sep 2004)
ISSN: 0047-1852 Japan |
| PMID | 15462392
(Publication Type: English Abstract, Journal Article, Review)
|
| Chemical References |
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| Topics |
- Antiparkinson Agents
(therapeutic use)
- Humans
- Parkinson Disease
(drug therapy)
|
