DNA vaccines against anthrax.

Abstract

DNA vaccination is vaccination at its simplest. Due to renewed interest in vaccination against anthrax and other biothreat agents, a genetic immunisation approach offers attractive possibilities for rapid, responsive vaccine development. DNA vaccination against anthrax is an active area of research showing promising results at present, which in the short-term and in the future could form the basis for new advances in multi-agent vaccine development. The anthrax 'model' constitutes an important experimental system for genetic immunisation technology development.

• Authors: Darrell R Galloway, Les Baillie
• Journal: Expert opinion on biological therapy (Expert Opin Biol Ther) Vol. 4 Issue 10 Pg. 1661-7 (Oct 2004) ISSN: 1744-7682 [Electronic] England
• PMID: 15461577 (Publication Type: Journal Article, Review)

Chemical References

• Anthrax Vaccines
• DNA, Bacterial
• Vaccines, DNA

Topics

• Animals
• Anthrax (prevention & control)
• Anthrax Vaccines (immunology)
• Bacillus anthracis (genetics, immunology)
• Bioterrorism
• Cattle
• Cattle Diseases (transmission)
• DNA, Bacterial (immunology)
• Drug Evaluation, Preclinical
• Female
• Humans
• Macaca mulatta
• Male
• Mice
• Plasmids (administration & dosage, genetics)
• Rabbits
• Vaccination
• Vaccines, DNA (immunology)