[Anti-Brucella antibody seroprevalence in blood donors for therapeutic ends at three blood banks of the Mexican Institute of Social Security].

Abstract

INTRODUCTION:

To determine seroprevalence for Brucella sp. in blood donors, a serologic study was carried out at three blood banks of the Instituto Mexicano del Seguro Social (IMSS).

METHODS:

500 blood samples were taken from selected blood donors. Laboratory tests were used, such as Bengal rose (BR), Standard agglutination in microplate (SAM) and in presence of 2-Mercaptoethanol agglutination in microplate (2ME), which were applied to 500 blood sera from selected effective blood donors. The sample was representative according to the statistical analysis developed.

RESULTS:

18 of 500 analyzed sera were positive, with seroprevalence of 3.6%, male sex (83.4%), predominating, as secondary activity group (72.2%). According to academic archivement, blood donors with secondary school had highest seropositivity (55.6%).

CONCLUSION:

In this study, we conclude that brucellosis has peculiar epidemiologic characteristics in blood banks that participated in this research; therefore it is highly recommended to perform screening tests such as BR, SAM, and 2ME to identified anti-Brucella antibodies in the sera of effective blood donors.

• Authors: Juan Carlos Torres-Padilla, Ahidé López-Merino, Rosa María García-Escamilla, José Natalio Gutiérrez-García
• Journal: Gaceta medica de Mexico (Gac Med Mex) 2004 Jul-Aug Vol. 140 Issue 4 Pg. 391-8 ISSN: 0016-3813 [Print] Mexico
• Vernacular Title: Seroprevalencia de anticuerpos anti-Brucella en disponentes de sangre con fines terapéuticos en tres bancos de sangre del Instituto Mexicano del Seguro Social.
• PMID: 15456149 (Publication Type: Comparative Study, English Abstract, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Antibodies, Bacterial

Topics

• Adolescent
• Adult
• Antibodies, Bacterial (blood)
• Blood Banks (statistics & numerical data)
• Blood Donors
• Brucella (immunology)
• Brucellosis (epidemiology, immunology)
• Female
• Humans
• Male
• Middle Aged
• Prevalence
• Seroepidemiologic Studies