SearchDictionaryMobileLogin

Polymerase chain reaction based detection of Mycobacterium tuberculosis complex in lupus vulgaris: a case report.

AbstractLupus vulgaris (LV), the commonest of all forms of cutaneous tuberculosis, can affect the earlobes. Authors present a 20-year-old male patient with LV of the left earlobe initially misdiagnosed as pyoderma and treated superfluously with antibiotics at different intervals over the last 4 years in another hospital. Mycobacteria could not be seen or isolated by stained smears or conventional or radiometric culture methods from the skin biopsy specimens. Suspected clinical diagnosis of our patient was LV. This was supported by positive polymerase chain reaction assay and histological findings. The lesion was treated successfully with anti-tuberculosis chemotherapy, further confirming the diagnosis of LV.
AuthorsO Baylan, E Arca, A Ozcan, O Kisa, A Albay, L Doganci (Affiliation: Department of Microbiology and Clinical Microbiology, Gulhane Military Medical Academy and Medical School, Ankara, Turkey. obaylan at gata.edu.tr)
JournalThe international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease (Int J Tuberc Lung Dis) Vol. 8 Issue 9 Pg. 1147-50 (Sep 2004) ISSN: 1027-3719 France
PMID15455604 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antitubercular Agents
  • DNA, Bacterial
Topics
  • Adult
  • Antitubercular Agents (therapeutic use)
  • DNA, Bacterial (analysis)
  • Diagnostic Errors
  • Ear, External (pathology)
  • Humans
  • Lupus Vulgaris (drug therapy, microbiology)
  • Male
  • Mycobacterium tuberculosis (genetics, pathogenicity)
  • Polymerase Chain Reaction
  • Pyoderma (diagnosis)
  • Treatment Outcome