[Percutaneous transhepatic intraportal administration of amphotericin B to a patient with multiple liver abscesses due to Candida albicans: with monitoring by fungal index as a parameter of Candida volume].

Abstract

A 59-year-old female with acute promyelocytic leukemia in remission was admitted to our center because of an episode of incidental high fever with general fatigue. She was found to have hepatomegaly. Abdominal CT revealed multiple liver abscesses and a positive culture was obtained for candida albicans from an aspirated abscess. She was treated with percutaneous transhepatic intraportal administration of amphotericin B in addition to oral and intravenous administration. We confirmed the remission of these abscesses by means of the fungal index which is the difference between the values of the limulus test and endotoxin specific test. The fungal index appears to be useful for early diagnosis and treatment of fungal infection.

• Authors: T Murayama, M Ito, S Imoto, T Takahashi, S Matozaki, T Nakagawa, T Isobe
• Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology (Rinsho Ketsueki) Vol. 33 Issue 1 Pg. 82-6 (Jan 1992) ISSN: 0485-1439 [Print] Japan
• PMID: 1545519 (Publication Type: Case Reports, Journal Article)

Chemical References

• Amphotericin B

Topics

• Amphotericin B (administration & dosage, therapeutic use)
• Candida albicans (isolation & purification)
• Candidiasis (drug therapy, microbiology)
• Female
• Humans
• Infusions, Intravenous
• Liver (microbiology)
• Liver Abscess (drug therapy, microbiology)
• Middle Aged
• Portal Vein