HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Phenotypic variation in hereditary nonpolyposis colon cancer syndrome. Association with infiltrative fibromatosis (desmoid tumor).

Abstract
Familial infiltrative fibromatosis (desmoid tumor) is a recognized complication of familial adenomatous polyposis (FAP) but has not been described in families without colonic polyposis. The authors describe a unique family in which a predisposition to infiltrative fibromatosis and nonpolyposis colon cancer was inherited dominantly through four generations. This report expands the range of phenotypic variation described for the hereditary nonpolyposis colon cancer (HNPCC) syndrome and adds to the extracolonic complications that are common with FAP and HNPCC.
AuthorsE R Maher, B Morson, R Beach, S V Hodgson
JournalCancer (Cancer) Vol. 69 Issue 8 Pg. 2049-51 (Apr 15 1992) ISSN: 0008-543X [Print] United States
PMID1544113 (Publication Type: Journal Article)
Topics
  • Adult
  • Colorectal Neoplasms, Hereditary Nonpolyposis (genetics)
  • Female
  • Fibroma (genetics)
  • Humans
  • Male
  • Middle Aged
  • Pedigree
  • Phenotype

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: