Abstract |
Streptovirudin (SV) in a concentration of 100 microng/ml reduced the multiplication of parainfluenza 3 virus by about 3.5 log units. When uninfected WISH cells were treated for 2 and 12 hours with 100 mug/ml of SV, 3H-thymidineincorporation was decreased, but no marked differences were observed in the incorporation of 3H-uridine. The level of intracellular cyclic adenosine monophosphate (c- AMP) was found to decrease in SV-treated cells.
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Authors | M Dobus, M Korbecki, S Szmigielski, J Rytko |
Journal | Acta virologica
(Acta Virol)
Vol. 21
Issue 1
Pg. 31-5
(Jan 1977)
ISSN: 0001-723X [Print] Slovakia |
PMID | 15435
(Publication Type: Journal Article)
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Chemical References |
- Anti-Bacterial Agents
- Antiviral Agents
- Glycine
- Thymidine
- Uridine
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Topics |
- Anti-Bacterial Agents
(pharmacology)
- Antiviral Agents
(pharmacology)
- Cells, Cultured
- Glycine
(metabolism)
- Parainfluenza Virus 3, Human
(drug effects, growth & development)
- Respirovirus
(drug effects)
- Streptomyces
- Thymidine
(metabolism)
- Uridine
(metabolism)
- Virus Replication
(drug effects)
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