Oxaflozane overdose in a child.

Abstract

A case of severe poisoning in a 2 year-old child who ingested 150 mg of oxaflozane, a non-tricyclic antidepressant, is reported. After loss of consciousness, opisthotonos and coma, recovery was obtained with conservative treatment. Atropine-like symptoms were noted. The maximal plasma concentration of oxaflozane was 63 ng/mL. The elimination half-life for N-dealkyloxaflozane was 4.8 h.

• Authors: J P Dutertre, P Barbier, A L Suc, A P Jonville, E Autret
• Journal: Journal of toxicology. Clinical toxicology (J Toxicol Clin Toxicol) Vol. 30 Issue 1 Pg. 123-6 ( 1992) ISSN: 0731-3810 [Print] United States
• PMID: 1542141 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antidepressive Agents
• Morpholines
• oxaflozane

Topics

• Antidepressive Agents (pharmacokinetics, poisoning)
• Child, Preschool
• Coma (chemically induced)
• Drug Overdose
• Half-Life
• Humans
• Male
• Morpholines (pharmacokinetics, poisoning)
• Muscle Hypertonia (chemically induced)