HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Sinonasal hemangiopericytomas. A clinicopathologic and DNA content study.

Abstract
The clinicopathologic and the flow cytometric DNA characteristics of 14 patients with sinonasal hemangiopericytomas are presented. Patient and tumor characteristics were similar to previously published series. Flow cytometric analysis revealed a diploid DNA pattern and low S-phase in 13 neoplasmas and an aneuploid DNA pattern with relatively high S-phase in one. Histopathologically, all diploid and low S-phase neoplasms displayed relatively uniform cellular features and low mitotic counts. All patients are alive and free of disease; one is still alive after a single recurrence. Our data suggest that sinonasal hemangiopericytomas are low-grade neoplasms as evidenced by their histomorphology and their DNA content. Recurrences are delayed and can be controlled.
AuthorsA K el-Naggar, J G Batsakis, G M Garcia, M L Luna, H Goepfert
JournalArchives of otolaryngology--head & neck surgery (Arch Otolaryngol Head Neck Surg) Vol. 118 Issue 2 Pg. 134-7 (Feb 1992) ISSN: 0886-4470 [Print] United States
PMID1540341 (Publication Type: Journal Article)
Chemical References
  • DNA, Neoplasm
Topics
  • Adult
  • Aged
  • Aged, 80 and over
  • DNA, Neoplasm (analysis)
  • Female
  • Flow Cytometry
  • Hemangiopericytoma (genetics, pathology)
  • Humans
  • Male
  • Middle Aged
  • Nose Neoplasms (genetics, pathology)
  • Paranasal Sinus Neoplasms (genetics, pathology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: