Abstract | BACKGROUND & AIMS: METHODS: RESULTS: In previous experiments, genistin absorption rate of 17.2% has been observed. In the present study, phloridzin administered simultaneously with genistin, increased genistin uptake 2.5 fold (44.5%). CONCLUSION: The naturally occurring substance phloridzin, present in apples, thus considerably amplify genistin absorption. These effects might offer a promising novel method in designing functional foods for cancer prevention by combining genistin- and phloridzin-containing foods.
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Authors | Wilfried Andlauer, Jochen Kolb, Peter Fürst |
Journal | Clinical nutrition (Edinburgh, Scotland)
(Clin Nutr)
Vol. 23
Issue 5
Pg. 989-95
(Oct 2004)
ISSN: 0261-5614 [Print] England |
PMID | 15380887
(Publication Type: Journal Article)
|
Chemical References |
- Isoflavones
- genistin
- Phlorhizin
|
Topics |
- Animals
- Food, Organic
- Intestinal Absorption
(drug effects)
- Intestine, Small
(metabolism)
- Isoflavones
(metabolism, pharmacokinetics)
- Male
- Neoplasms
(prevention & control)
- Phlorhizin
(pharmacology)
- Rats
- Rats, Sprague-Dawley
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