Antenna coupling microwave plasma enables a highly efficient and oxidative treatment of the outermost surface of
polypropylene (PP) non-woven fabric within a short time period. Subsequently, grafting copolymerization with
acrylic acid (AAc) makes the plasma-treated fabric durably hydrophilic and excellent in water absorbency. With high grafting density and strong water affinity, the pAAc-grafted fabric greatly becomes feasible as an intensive absorbent and as a support to promote
chitosan-immobilization through
amide bonds. Experimental result demonstrated that surface analyses by FTIR-ATR have shown that R-CONH-R',
amide binding were emerged between pAAc and
chitosan. The XPS measurements on C(1s) 286.0 eV (C-
OH), 286.5 eV (C-N) and 288.1 eV (O=C-NH) also could be found. Bioactivity assessments on the
chitosan-immobilized surfaces were anticipated by activated partial thromboplastin time (aPTT), thrombin time (TT), and
fibrinogen concentration. By means of cell counter we counted the ratio of blood cell adhesion on the modified fabric matrix. After human plasma incubated with the
chitosan-immobilized PP fabrics, the required time for aPTT and blood cell adhesion increased significantly, while
fibrinogen concentration and TT did not change. Due to the capability of anticoagulation and cell adhesion, the
chitosan-immobilized PP fabric can be used as the substrate for cell culturing and then developed the
wound-dressing substitute for second-degree
burn.