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Anti-Ri antibody opsoclonus-myoclonus syndrome and breast cancer: a case report and a review of the literature.

AbstractOpsoclonus-myoclonus is a rare neurological paraneoplastic syndrome associated with breast cancer and the presence of anti-Ri antibody. We presented a case of a 79-year-old woman with this syndrome and a small invasive ductal carcinoma [pT1aN0(sn)M0], whose symptoms improved 3 months following her simple mastectomy without any adjuvant therapy. Based on the 15 previously reported cases in the literature, there is no uniform treatment option available, and the response to such treatments is mixed.
AuthorsDavid A Weizman, Wey L Leong (Affiliation: General Surgery and Surgical Oncology, Princess Margaret Hospital, University Health Network, Toronto, ON, Canada.)
JournalJournal of surgical oncology (J Surg Oncol) Vol. 87 Issue 3 Pg. 143-5 (Sep 1 2004) ISSN: 0022-4790 United States
PMID15334643 (Publication Type: Case Reports, Journal Article, Review)
CopyrightCopyright 2004 Wiley-Liss, Inc.
Chemical References
  • Antigens, Neoplasm
  • Autoantibodies
  • Nerve Tissue Proteins
  • Nova antigen
  • RNA-Binding Proteins
Topics
  • Aged
  • Antigens, Neoplasm (immunology)
  • Autoantibodies (analysis)
  • Breast Neoplasms (complications, surgery)
  • Carcinoma, Ductal, Breast (complications, surgery)
  • Female
  • Humans
  • Nerve Tissue Proteins (immunology)
  • Paraneoplastic Syndromes, Nervous System (complications, immunology)
  • Purkinje Cells (immunology)
  • RNA-Binding Proteins (immunology)